Publications

Selected Highlights

Sperm chromatin accessibility’s involvement in the intergenerational effects of stress hormone receptor activation.

Fischer V, Kretschmer M, Germain PL, Kaur J, Mompart-Barrenechea S, Pelczar P, Schürmann D, Schłr P, Gapp K. Transl Psychiatry. 2023 Dec 8;13(1):378. doi: 10.1038/s41398-023-02684-z

Gasdermin D is the only Gasdermin that provides protection against acute Salmonella gut infection in mice.

Fattinger SA, Maurer L, Geiser P, Bernard EM, Enz U, Ganguillet S, Gül E, Kroon S, Demarco B, Mack V, Furter M, Barthel M, Pelczar P, Shao F, Broz P, Sellin ME, Hardt WD. Proc Natl Acad Sci U S A. 2023 Nov 28;120(48):e2315503120. doi: 10.1073/pnas.2315503120

TNF-alpha protects from exacerbated myocarditis and cardiac death by suppressing expansion of activated heart-reactive CD4+ T cells.

Rolski F, Tkacz K, Węglarczyk K, Kwiatkowski G, Pelczar P, Jaźwa-Kusior A, Bar A, Kuster GM, Chłopicki S, Siedlar M, Kania G, Błyszczuk P. Cardiovasc Res. 2023 Oct 25. pii: cvad158. doi: 10.1093/cvr/cvad158

GPR182 is a broadly scavenging atypical chemokine receptor influencing T-independent immunity.

Melgrati S, Gerken OJ, Artinger M, Radice E, Szpakowska M, Chevigné A, D’Uonnolo G, Antonello P, Thelen S, Pelczar P, Legler DF, Thelen M. Front Immunol. 2023 Jul 24;14:1242531. doi: 10.3389/fimmu.2023.1242531

Atlas of the anatomical localization of atypical chemokine receptors in healthy mice.

Melgrati S, Radice E, Ameti R, Hub E, Thelen S, Pelczar P, Jarrossay D, Rot A, Thelen M. PLoS Biol. 2023 May 9;21(5):e3002111. doi: 10.1371/journal.pbio.3002111

Nerve pathology is prevented by linker proteins in mouse models for LAMA2-related muscular dystrophy.

Reinhard JR, Porrello E, Lin S, Pelczar P, Previtali SC, Rüegg MA. PNAS Nexus. 2023 Mar 15;2(4):pgad083. doi: 10.1093/pnasnexus/pgad083

c-Maf-positive spinal cord neurons are critical elements of a dorsal horn circuit for mechanical hypersensitivity in neuropathy.

Frezel N, Ranucci M, Foster E, Wende H, Pelczar P, Mendes R, Ganley RP, Werynska K, d’Aquin S, Beccarini C, Birchmeier C, Zeilhofer HU, Wildner H. Cell Rep. 2023 Apr 25;42(4):112295. doi: 10.1016/j.celrep.2023.112295

Inhibitory Kcnip2 neurons of the spinal dorsal horn control behavioral sensitivity to environmental cold.

Albisetti GW, Ganley RP, Pietrafesa F, Werynska K, Magalhaes de Sousa M, Sipione R, Scheurer L, Bösl MR, Pelczar P, Wildner H, Zeilhofer HU. Neuron. 2023 Jan 4;111(1):92-105.e5. doi: 10.1016/j.neuron.2022.10.008

Defective Desmosomal Adhesion Causes Arrhythmogenic Cardiomyopathy by Involving an Integrin-αVβ6/TGF-β Signaling Cascade.

Schinner C, Xu L, Franz H, Zimmermann A, Wanuske MT, Rathod M, Hanns P, Geier F, Pelczar P, Liang Y, Lorenz V, Stüdle C, Maly PI, Kauferstein S, Beckmann BM, Sheikh F, Kuster GM, Spindler V. Circulation. 2022 Nov 22;146(21):1610-1626. doi: 10.1161/CIRCULATIONAHA.121.057329

Dntt expression reveals developmental hierarchy and lineage specification of hematopoietic progenitors.

Klein F, Roux J, Cvijetic G, Rodrigues PF, von Muenchow L, Lubin R, Pelczar P, Yona S, Tsapogas P, Tussiwand R. Nat Immunol. 2022 Apr;23(4):505-517. doi: 10.1038/s41590-022-01167-5

Glial activation in prion diseases is selectively triggered by neuronal PrP(Sc).

Lakkaraju AKK, Sorce S, Senatore A, Nuvolone M, Guo J, Schwarz P, Moos R, Pelczar P, Aguzzi A. Brain Pathol. 2022 Sep;32(5):e13056. doi: 10.1111/bpa.13056

GPR180 is a component of TGFβ signalling that promotes thermogenic adipocyte function and mediates the metabolic effects of the adipocyte-secreted factor CTHRC1.

Balazova L, Balaz M, Horvath C, Horváth Á, Moser C, Kovanicova Z, Ghosh A, Ghoshdastider U, Efthymiou V, Kiehlmann E, Sun W, Dong H, Ding L, Amri EZ, Nuutila P, Virtanen KA, Niemi T, Ukropcova B, Ukropec J, Pelczar P, Lamla T, Hamilton B, et al. Nat Commun. 2021 Dec 8;12(1):7144. doi: 10.1038/s41467-021-27442-x

Neuron-specific spinal cord translatomes reveal a neuropeptide code for mouse dorsal horn excitatory neurons.

Das Gupta RR, Scheurer L, Pelczar P, Wildner H, Zeilhofer HU. Sci Rep. 2021 Mar 4;11(1):5232. doi: 10.1038/s41598-021-84667-y

Boundary sequences flanking the mouse tyrosinase locus ensure faithful pattern of gene expression.

Seruggia D, Fernández A, Cantero M, Fernández-Miñán A, Gomez-Skarmeta JL, Pelczar P, Montoliu L. Sci Rep. 2020 Sep 23;10(1):15494. doi: 10.1038/s41598-020-72543-0

Magnetic fields modulate metabolism and gut microbiome in correlation with Pgc-1α expression: Follow-up to an in vitro magnetic mitohormetic study.

Tai YK, Ng C, Purnamawati K, Yap JLY, Yin JN, Wong C, Patel BK, Soong PL, Pelczar P, Fröhlich J, Beyer C, Fong CHH, Ramanan S, Casarosa M, Cerrato CP, Foo ZL, Pannir Selvan RM, Grishina E, Degirmenci U, Toh SJ, Richards PJ, Mirsaidi A, et al. FASEB J. 2020 Aug;34(8):11143-11167. doi: 10.1096/fj.201903005RR

Bi-allelic expression of the RyR1 p.A4329D mutation decreases muscle strength in slow-twitch muscles in mice.

Elbaz M, Ruiz A, Nicolay S, Tupini C, Bachmann C, Eckhardt J, Benucci S, Pelczar P, Treves S, Zorzato F. J Biol Chem. 2020 Jul 24;295(30):10331-10339. doi: 10.1074/jbc.RA120.013846

Palmitoylation of BMPR1a regulates neural stem cell fate.

Wegleiter T, Buthey K, Gonzalez-Bohorquez D, Hruzova M, Bin Imtiaz MK, Abegg A, Mebert I, Molteni A, Kollegger D, Pelczar P, Jessberger S. Proc Natl Acad Sci U S A. 2019 Dec 17;116(51):25688-25696. doi: 10.1073/pnas.1912671116

Topical application of human-derived Ig isotypes for the control of acute respiratory infection evaluated in a human CD89-expressing mouse model.

Koernig S, Campbell IK, Mackenzie-Kludas C, Schaub A, Loetscher M, Ching Ng W, Zehnder R, Pelczar P, Sanli I, Alhamdoosh M, Ng M, Brown LE, Kłsermann F, Vonarburg C, Zuercher AW. Mucosal Immunol. 2019 Jul;12(4):1013-1024. doi: 10.1038/s41385-019-0167-z

Fate-Mapping of GM-CSF Expression Identifies a Discrete Subset of Inflammation-Driving T Helper Cells Regulated by Cytokines IL-23 and IL-1β.

Komuczki J, Tuzlak S, Friebel E, Hartwig T, Spath S, Rosenstiel P, Waisman A, Opitz L, Oukka M, Schreiner B, Pelczar P, Becher B. Immunity. 2019 May 21;50(5):1289-1304.e6. doi: 10.1016/j.immuni.2019.04.006

Maternal overnutrition programs hedonic and metabolic phenotypes across generations through sperm tsRNAs.

Sarker G, Sun W, Rosenkranz D, Pelczar P, Opitz L, Efthymiou V, Wolfrum C, Peleg-Raibstein D. Proc Natl Acad Sci U S A. 2019 May 21;116(21):10547-10556. doi: 10.1073/pnas.1820810116

Quantitative RyR1 reduction and loss of calcium sensitivity of RyR1Q1970fsX16+A4329D cause cores and loss of muscle strength.

Elbaz M, Ruiz A, Bachmann C, Eckhardt J, Pelczar P, Venturi E, Lindsay C, Wilson AD, Alhussni A, Humberstone T, Pietrangelo L, Boncompagni S, Sitsapesan R, Treves S, Zorzato F. Hum Mol Genet. 2019 Sep 15;28(18):2987-2999. doi: 10.1093/hmg/ddz092

Extrinsic and intrinsic apoptosis activate pannexin-1 to drive NLRP3 inflammasome assembly.

Chen KW, Demarco B, Heilig R, Shkarina K, Boettcher A, Farady CJ, Pelczar P, Broz P. EMBO J. 2019 May 15;38(10). pii: e101638. doi: 10.15252/embj.2019101638

The transcription factor Duxbl mediates elimination of pre-T cells that fail β-selection.

Klein F, Mitrovic M, Roux J, Engdahl C, von Muenchow L, Alberti-Servera L, Fehling HJ, Pelczar P, Rolink A, Tsapogas P. J Exp Med. 2019 Mar 4;216(3):638-655. doi: 10.1084/jem.20181444

Quantitative reduction of RyR1 protein caused by a single-allele frameshift mutation in RYR1 ex36 impairs the strength of adult skeletal muscle fibres.

Elbaz M, Ruiz A, Eckhardt J, Pelczar P, Muntoni F, Boncompagni S, Treves S, Zorzato F. Hum Mol Genet. 2019 Jun 1;28(11):1872-1884. doi: 10.1093/hmg/ddz025

Primed Track, high-fidelity lineage tracing in mouse pre-implantation embryos using primed conversion of photoconvertible proteins.

Welling M, Mohr MA, Ponti A, Rullan Sabater L, Boni A, Kawamura YK, Liberali P, Peters AH, Pelczar P, Pantazis P. Elife. 2019 Jan 21;8. pii: e44491. doi: 10.7554/eLife.44491

A Transgenic MMTV-Flippase Mouse Line for Molecular Engineering in Mammary Gland and Breast Cancer Mouse Models.

Lüönd F, Bill R, Vettiger A, Oller H, Pelczar P, Christofori G. J Mammary Gland Biol Neoplasia. 2019 Mar;24(1):39-45. doi: 10.1007/s10911-018-9412-4

Transgenerational transmission of hedonic behaviors and metabolic phenotypes induced by maternal overnutrition.

Sarker G, Berrens R, von Arx J, Pelczar P, Reik W, Wolfrum C, Peleg-Raibstein D. Transl Psychiatry. 2018 Oct 12;8(1):195. doi: 10.1038/s41398-018-0243-2

Author Correction: Cold-induced epigenetic programming of the sperm enhances brown adipose tissue activity in the offspring.

Sun W, Dong H, Becker AS, Dapito DH, Modica S, Grandl G, Opitz L, Efthymiou V, Straub LG, Sarker G, Balaz M, Balazova L, Perdikari A, Kiehlmann E, Bacanovic S, Zellweger C, Peleg-Raibstein D, Pelczar P, Reik W, Burger IA, von Meyenn F, Wolfrum C. Nat Med. 2018 Nov;24(11):1776. doi: 10.1038/s41591-018-0162-z

Publisher Correction: Cold-induced epigenetic programming of the sperm enhances brown adipose tissue activity in the offspring.

Sun W, Dong H, Becker AS, Dapito DH, Modica S, Grandl G, Opitz L, Efthymiou V, Straub LG, Sarker G, Balaz M, Balazova L, Perdikari A, Kiehlmann E, Bacanovic S, Zellweger C, Peleg-Raibstein D, Pelczar P, Reik W, Burger IA, von Meyenn F, Wolfrum C. Nat Med. 2018 Nov;24(11):1777. doi: 10.1038/s41591-018-0163-y

Cold-induced epigenetic programming of the sperm enhances brown adipose tissue activity in the offspring.

Sun W, Dong H, Becker AS, Dapito DH, Modica S, Grandl G, Opitz L, Efthymiou V, Straub LG, Sarker G, Balaz M, Balazova L, Perdikari A, Kiehlmann E, Bacanovic S, Zellweger C, Peleg-Raibstein D, Pelczar P, Reik W, Burger IA, von Meyenn F, Wolfrum C. Nat Med. 2018 Sep;24(9):1372-1383. doi: 10.1038/s41591-018-0102-y

TRPC1 regulates brown adipose tissue activity in a PPARγ-dependent manner.

Wolfrum C, Kiehlmann E, Pelczar P. Am J Physiol Endocrinol Metab. 2018 Nov 1;315(5):E825-E832. doi: 10.1152/ajpendo.00170.2017

LPS targets host guanylate-binding proteins to the bacterial outer membrane for non-canonical inflammasome activation.

Santos JC, Dick MS, Lagrange B, Degrandi D, Pfeffer K, Yamamoto M, Meunier E, Pelczar P, Henry T, Broz P. EMBO J. 2018 Mar 15;37(6). pii: e98089. doi: 10.15252/embj.201798089

Corrigendum: Pramel7 mediates ground-state pluripotency through proteasomal-epigenetic combined pathways.

Graf U, Casanova EA, Wyck S, Dalcher D, Gatti M, Vollenweider E, Okoniewski MJ, Weber FA, Patel SS, Schmid MW, Li J, Sharif J, Wanner GA, Koseki H, Wong J, Pelczar P, Penengo L, Santoro R, Cinelli P. Nat Cell Biol. 2017 Jul 28;19(8):1003. doi: 10.1038/ncb3572

Pramel7 mediates ground-state pluripotency through proteasomal-epigenetic combined pathways.

Graf U, Casanova EA, Wyck S, Dalcher D, Gatti M, Vollenweider E, Okoniewski MJ, Weber FA, Patel SS, Schmid MW, Li J, Sharif J, Wanner GA, Koseki H, Wong J, Pelczar P, Penengo L, Santoro R, Cinelli P. Nat Cell Biol. 2017 Jul;19(7):763-773. doi: 10.1038/ncb3554

Regulated expression of amyloidogenic immunoglobulin light chains in mice.

Nuvolone M, Sorce S, Pelczar P, Rushing E, Lavatelli F, Rognoni P, Valentini V, Palladini G, Merlini G, Aguzzi A. Amyloid. 2017 Mar;24(sup1):52-53. doi: 10.1080/13506129.2017.1289914

Efficient Generation of Multi-gene Knockout Cell Lines and Patient-derived Xenografts Using Multi-colored Lenti-CRISPR-Cas9.

Behrmann L, McComb S, Aguadé-Gorgorió J, Huang Y, Hermann M, Pelczar P, Aguzzi A, Bourquin JP, Bornhauser BC. Bio Protoc. 2017 Apr 5;7(7):e2222. doi: 10.21769/BioProtoc.2222

Dysregulation of the Cytokine GM-CSF Induces Spontaneous Phagocyte Invasion and Immunopathology in the Central Nervous System.

Spath S, Komuczki J, Hermann M, Pelczar P, Mair F, Schreiner B, Becher B. Immunity. 2017 Feb 21;46(2):245-260. doi: 10.1016/j.immuni.2017.01.007

Protease resistance of infectious prions is suppressed by removal of a single atom in the cellular prion protein.

Leske H, Hornemann S, Herrmann US, Zhu C, Dametto P, Li B, Laferriere F, Polymenidou M, Pelczar P, Reimann RR, Schwarz P, Rushing EJ, Wüthrich K, Aguzzi A. PLoS One. 2017 Feb 16;12(2):e0170503. doi: 10.1371/journal.pone.0170503

Modeling the ferrochelatase c.315-48C modifier mutation for erythropoietic protoporphyria (EPP) in mice.

Barman-Aksözen J, C Wiek P, Bansode VB, Koentgen F, Trüb J, Pelczar P, Cinelli P, Schneider-Yin X, Schümperli D, Minder EI. Dis Model Mech. 2017 Mar 1;10(3):225-233. doi: 10.1242/dmm.027755

Strictly co-isogenic C57BL/6J-Prnp-/- mice: A rigorous resource for prion science.

Nuvolone M, Hermann M, Sorce S, Russo G, Tiberi C, Schwarz P, Minikel E, Sanoudou D, Pelczar P, Aguzzi A. J Exp Med. 2016 Mar 7;213(3):313-27. doi: 10.1084/jem.20151610

Continuous Histone Replacement by Hira Is Essential for Normal Transcriptional Regulation and De Novo DNA Methylation during Mouse Oogenesis.

Nashun B, Hill PW, Smallwood SA, Dharmalingam G, Amouroux R, Clark SJ, Sharma V, Ndjetehe E, Pelczar P, Festenstein RJ, Kelsey G, Hajkova P. Mol Cell. 2015 Nov 19;60(4):611-25. doi: 10.1016/j.molcel.2015.10.010

The Cytokine GM-CSF Drives the Inflammatory Signature of CCR2+ Monocytes and Licenses Autoimmunity.

Croxford AL, Lanzinger M, Hartmann FJ, Schreiner B, Mair F, Pelczar P, Clausen BE, Jung S, Greter M, Becher B. Immunity. 2015 Sep 15;43(3):502-14. doi: 10.1016/j.immuni.2015.08.010

Functional validation of mouse tyrosinase non-coding regulatory DNA elements by CRISPR-Cas9-mediated mutagenesis.

Seruggia D, Fernández A, Cantero M, Pelczar P, Montoliu L. Nucleic Acids Res. 2015 May 26;43(10):4855-67. doi: 10.1093/nar/gkv375

Neurodegeneration and unfolded-protein response in mice expressing a membrane-tethered flexible tail of PrP.

Dametto P, Lakkaraju AK, Bridel C, Villiger L, O’Connor T, Herrmann US, Pelczar P, Rülicke T, McHugh D, Adili A, Aguzzi A. PLoS One. 2015 Feb 6;10(2):e0117412. doi: 10.1371/journal.pone.0117412

Mouse genome engineering using designer nucleases.

Hermann M, Cermak T, Voytas DF, Pelczar P. J Vis Exp. 2014 Apr 2;(86). doi: 10.3791/50930

Implication of sperm RNAs in transgenerational inheritance of the effects of early trauma in mice.

Gapp K, Jawaid A, Sarkies P, Bohacek J, Pelczar P, Prados J, Farinelli L, Miska E, Mansuy IM. Nat Neurosci. 2014 May;17(5):667-9. doi: 10.1038/nn.3695

Heritable and inducible gene knockdown in astrocytes or neurons in vivo by a combined lentiviral and RNAi approach.

Heitz F, Johansson T, Baumgłrtel K, Gecaj R, Pelczar P, Mansuy IM. Front Cell Neurosci. 2014 Mar 19;8:62. doi: 10.3389/fncel.2014.00062

Binary recombinase systems for high-resolution conditional mutagenesis.

Hermann M, Stillhard P, Wildner H, Seruggia D, Kapp V, Sánchez-Iranzo H, Mercader N, Montoliu L, Zeilhofer HU, Pelczar P. Nucleic Acids Res. 2014 Apr;42(6):3894-907. doi: 10.1093/nar/gkt1361

Stroma-derived interleukin-34 controls the development and maintenance of langerhans cells and the maintenance of microglia.

Greter M, Lelios I, Pelczar P, Hoeffel G, Price J, Leboeuf M, Kündig TM, Frei K, Ginhoux F, Merad M, Becher B. Immunity. 2012 Dec 14;37(6):1050-1060. doi: 10.1016/j.immuni.2012.11.001

Hyperactive self-inactivating piggyBac for transposase-enhanced pronuclear microinjection transgenesis.

Marh J, Stoytcheva Z, Urschitz J, Sugawara A, Yamashiro H, Owens JB, Stoytchev I, Pelczar P, Yanagimachi R, Moisyadi S. Proc Natl Acad Sci U S A. 2012 Nov 20;109(47):19184-9. doi: 10.1073/pnas.1216473109

Evaluation of OPEN zinc finger nucleases for direct gene targeting of the ROSA26 locus in mouse embryos.

Hermann M, Maeder ML, Rector K, Ruiz J, Becher B, Bürki K, Khayter C, Aguzzi A, Joung JK, Buch T, Pelczar P. PLoS One. 2012;7(9):e41796. doi: 10.1371/journal.pone.0041796

Pramel7 mediates LIF/STAT3-dependent self-renewal in embryonic stem cells.

Casanova EA, Shakhova O, Patel SS, Asner IN, Pelczar P, Weber FA, Graf U, Sommer L, Bürki K, Cinelli P. Stem Cells. 2011 Mar;29(3):474-85. doi: 10.1002/stem.588

Specific proteolytic cleavage of agrin regulates maturation of the neuromuscular junction.

Bolliger MF, Zurlinden A, Lüscher D, Bütikofer L, Shakhova O, Francolini M, Kozlov SV, Cinelli P, Stephan A, Kistler AD, Rülicke T, Pelczar P, Ledermann B, Fumagalli G, Gloor SM, Kunz B, Sonderegger P. J Cell Sci. 2010 Nov 15;123(Pt 22):3944-55. doi: 10.1242/jcs.072090

Helper-independent piggyBac plasmids for gene delivery approaches: strategies for avoiding potential genotoxic effects.

Urschitz J, Kawasumi M, Owens J, Morozumi K, Yamashiro H, Stoytchev I, Marh J, Dee JA, Kawamoto K, Coates CJ, Kaminski JM, Pelczar P, Yanagimachi R, Moisyadi S. Proc Natl Acad Sci U S A. 2010 May 4;107(18):8117-22. doi: 10.1073/pnas.1003674107

A novel three-dimensional culture system allows prolonged culture of functional human granulosa cells and mimics the ovarian environment.

Kossowska-Tomaszczuk K, Pelczar P, Güven S, Kowalski J, Volpi E, De Geyter C, Scherberich A. Tissue Eng Part A. 2010 Jun;16(6):2063-73. doi: 10.1089/ten.TEA.2009.0684

Genetic vasectomy-overexpression of Prm1-EGFP fusion protein in elongating spermatids causes dominant male sterility in mice.

Haueter S, Kawasumi M, Asner I, Brykczynska U, Cinelli P, Moisyadi S, Bürki K, Peters AH, Pelczar P. Genesis. 2010 Mar;48(3):151-60. doi: 10.1002/dvg.20598

High survival and developmental rates of vitrified mouse zygotes following polar body biopsy.

Macas E, Merki-Feld GS, Xie M, Stiller R, Pelczar P, Imthurn B. Reprod Biomed Online. 2008 Feb;16(2):271-5. doi: 10.1016/s1472-6483(10)60585-8

Active integration: new strategies for transgenesis.

Shinohara ET, Kaminski JM, Segal DJ, Pelczar P, Kolhe R, Ryan T, Coates CJ, Fraser MJ, Handler AM, Yanagimachi R, Moisyadi S. Transgenic Res. 2007 Jun;16(3):333-9. Epub 2007 Mar 6. doi: 10.1007/s11248-007-9077-z

Chromosome-wide nucleosome replacement and H3.3 incorporation during mammalian meiotic sex chromosome inactivation.

van der Heijden GW, Derijck AA, Pósfai E, Giele M, Pelczar P, Ramos L, Wansink DG, van der Vlag J, Peters AH, de Boer P. Nat Genet. 2007 Feb;39(2):251-8. Epub 2007 Jan 21. doi: 10.1038/ng1949

The physiological and behavioral impact of sensory contact among unfamiliar adult mice in the laboratory.

Rettich A, Kłsermann HP, Pelczar P, Bürki K, Arras M. J Appl Anim Welf Sci. 2006;9(4):277-88. doi: 10.1207/s15327604jaws0904_3

piggyBac is a flexible and highly active transposon as compared to sleeping beauty, Tol2, and Mos1 in mammalian cells.

Wu SC, Meir YJ, Coates CJ, Handler AM, Pelczar P, Moisyadi S, Kaminski JM. Proc Natl Acad Sci U S A. 2006 Oct 10;103(41):15008-13. Epub 2006 Sep 27. doi: 10.1073/pnas.0606979103

Tn5 transposase-mediated mouse transgenesis.

Suganuma R, Pelczar P, Spetz JF, Hohn B, Yanagimachi R, Moisyadi S. Biol Reprod. 2005 Dec;73(6):1157-63. Epub 2005 Aug 3. doi: 10.1095/biolreprod.105.044669

Recombinase-mediated mouse transgenesis by intracytoplasmic sperm injection.

Kaneko T, Moisyadi S, Suganuma R, Hohn B, Yanagimachi R, Pelczar P. Theriogenology. 2005 Nov;64(8):1704-15. Epub 2005 Jun 9. Erratum in: Theriogenology. 2006 Jul 15;66(2):494. doi: 10.1016/j.theriogenology.2005.04.003

High frequency of nucleotide misincorporations upon the processing of double-strand breaks.

Kovalchuk I, Pelczar P, Kovalchuk O. DNA Repair (Amst). 2004 Mar 4;3(3):217-23. doi: 10.1016/j.dnarep.2003.09.011

Agrobacterium proteins VirD2 and VirE2 mediate precise integration of synthetic T-DNA complexes in mammalian cells.

Pelczar P, Kalck V, Gomez D, Hohn B. EMBO Rep. 2004 Jun;5(6):632-7. Epub 2004 May 21. doi: 10.1038/sj.embor.7400165

Different genome maintenance strategies in human and tobacco cells.

Pelczar P, Kalck V, Kovalchuk I. J Mol Biol. 2003 Aug 22;331(4):771-9. doi: 10.1016/s0022-2836(03)00839-8

An Agrobacterium VirE2 channel for transferred-DNA transport into plant cells

Dumas, F., Duckely M. ,Pelczar P., Van Gelder P., Hohn B. PNAS 98, 485-490 (2001). doi: 10.1073/pnas.98.2.485

Structure and biogenesis of small nucleolar RNAs acting as guides for ribosomal RNA modification

Filipowicz, W., Pelczar, P., Pogacic, V. & Dragon, F Acta Biochim Pol. 1999;46(2):377-89 PMID: 10547039

The host gene for intronic U17 small nucleolar RNAs in mammals has no protein-coding potential and is a member of the 5′-terminal oligopyrimidine gene family.

Pelczar, P & Filipowicz, W. Mol Cell Biol. 1998 Aug;18(8):4509-18. doi: 10.1128/MCB.18.8.4509.

How many 5S rRNA genes and pseudogenes are there in Aspergillus nidulans?

Pelczar P, Fiett J, Bartnik E. Acta Biochim Pol. 1994;41(4):449-52. PMID: 7732763